My name is Edward Emmott and I am a postdoc in Nikolai Slavovs lab at Northeastern University. My current work involves studying ribosome heterogeneity, and the interaction of the immune system with protein synthesis. I am also involved in the labs efforts to further develop and apply single cell proteomics (SCoPE-MS). My past work has involved researching positive-sense RNA viruses – most recently norovirus, the cause of ‘winter vomiting disease’.

I’m interested in how viruses replicate and interact with their host, as well as how host cells defend against and adapt to viral infection. By understanding these processes, we can identify new drug targets, or use this information to design vaccines.

For more details please see about me, or my publications.

New preprint – Ribosome stoichiometry: from form to function

I have a new preprint out with Marko Jovanovic (Columbia U.) and Nikolai Slavov. In it we review the evidence in favor of the existenceRead More →

Supporting preprints!

I wrote a short piece for ‘We support preprints’ on how I think preprints are helping advance biology, and how they are particularly useful forRead More →

IFIT paper out!

Fleith & Mears et. al. paper on IFIT-based translation inhibition now accepted in Nucleic Acids Research. The paper shows how homo- and heteromeric interactions betweenRead More →

Norovirus protease inhibitor paper out!

New paper by Mitsutaka Kitano now out! Uses human norovirus replicons and cell-based FRET protease sensors to study the acquisition of resistance mutants to theRead More →

Preprint – Norovirus precursor proteins

We just published a new preprint in bioRxiv. We study how norovirus polyprotein precursors containing the norovirus protease (NS6) confer protein:protein interactions and localisation uponRead More →