My name is Edward Emmott and I am a postdoc in Nikolai Slavovs lab at Northeastern University. My current work involves studying ribosome heterogeneity, and the interaction of the immune system with protein synthesis. I am also involved in the lab’s efforts to further develop and apply single cell proteomics (SCoPE-MS). My past work has involved researching positive-sense RNA viruses – most recently norovirus, the cause of ‘winter vomiting disease’.

I’m interested in how viruses replicate and interact with their host, as well as how host cells defend against and adapt to viral infection. By understanding these processes, we can identify new drug targets, or use this information to design vaccines.

For more details please see about me, or my publications.

Tandem Mass Tag Research Award!

Ed was awarded one of four Tandem Mass Tag Research awards. These are an annual international award by Thermo Scientific given on the basis of ‘innovative and impactful’ research in Proteomics. Ed will be using his TMT research award toRead More →

New preprint – Ribosome stoichiometry: from form to function

I have a new preprint out with Marko Jovanovic (Columbia U.) and Nikolai Slavov. In it we review the evidence in favor of the existence of functionally specialized ribosomes, and discuss the approaches and tests that will allow confirmation ofRead More →

Supporting preprints!

I wrote a short piece for ‘We support preprints’ on how I think preprints are helping advance biology, and how they are particularly useful for early career researchers. The article can be found at https://wesupportpreprints.wordpress.com/Read More →

IFIT paper out!

Fleith & Mears et. al. paper on IFIT-based translation inhibition now accepted in Nucleic Acids Research. The paper shows how homo- and heteromeric interactions between IFIT family members influence RNA-binding and thus translation inhibition. JournalRead More →

Preprint – Norovirus precursor proteins

We just published a new preprint in bioRxiv. We study how norovirus polyprotein precursors containing the norovirus protease (NS6) confer protein:protein interactions and localisation upon the protease. This regulates the ability of the protease to access specific substrates. As theRead More →